African tale of Action Potential "the story of thought"

[Pragmatic]

Action Potential

By

Michael Brown

“a true story of thought in process”

One day, “thought” went traveling deep inside of the central nervous system looking for mitochondrion. Thought loved them so! Every time “thought” went traveling it needed these “long cellular organelles” if it were to make it outside of the nucleus. They were soooo rich in fats, and proteins that one needed very little or you would be to “big” to fit inside of the “soma”, that’s were all the nucleus lived and you had to be small to live in there.

Even though there were diverse populations using “different” neurotransmitters to communicate; some big, some small; any change to the cell’s membrane could change the absolute value of there civilization known as “interphase” which would increase or decrease the life expectancy of the membrane potential to zero which then cause the cell to hyperpolarize and die.

They, the “sensory neurons” have always lived close to together in the “Kingdom of Ganglia” and the Emperor Plexus was crowned the The “Asantehene” over the entire “central nervous system” to once again restore the “Palace” to it’s once stable empire.

After being "crowned" on the “Golden stool” which contained the “brain and spinal cord” he immediately provided “relay points” and “intermediary connections” to his complex system to govern pre and postsynaptic transmissions.

The “Assatehene” is “very wise” but “stern”. When it comes down to “neurotransmitters” being released across the “synaptic cleft” it just flat out causes him to have “nervous impulses” every time. Nothing ever goes unchecked in his palace. Nothing’!!

The Emperor’s central nervous system was protected by none other than the most famous general in the whole land’ General Oligodendrocytes, and under his command Lt. Swhann, who worked the “peripheral” side of the kingdom.

General Oligodendrocytes and Lt. Swhanns’ “neuroglia” insulate and protect the “axon”. (The neuroglia are the king’s army that make a myelin sheath; a shield of fat-containing cells that insulate the axon from electrical activity) and ol’ did they eat handsomely!!!

General Oli~go~dend~ro~cytes, protector of the Golden Stool was “put-in” charge by the Asantehene to increase the rate of transmission of signals. A gap, which exists between each myelin sheath propagates agation of electricity; this helps the signal jump from one gap to the next to further enhance daily operations between the community‘s.

The gaps are governed by “Exocytosis of the Samburu tribe” who ensures that soluble proteins will be secreted throughout the land of Ganglia, the safe travel of interneuronal signaling for serotonin, histamine, and dopamine, keeps the kingdom rested and alert ready for war!


Around the kingdom the King has made the customary action of “hopping” or salutatory conduction, mandatory for years because myelin inhibits charge leakage of sodium and potassium positively and negatively charged ions. This is where most of the imbalance happens but was promptly corrected as the Emperor saw fit to install a sodium potassium pump which made our impulses faster across the “Nodes of Ranvier”. We used to be so exhausted transmitting information because the Queen Hypothalamus, of the Nyabinghi “never slept” and if you crossed her, she would send the hound “Dopamine” to keep you stuck in membrane until “re-uptake” or worst degradation were you would wither away due to stress and lack of regeneration of energy.

The central nervous system of the kingdom contains the majority of the nervous system, and the “Golden stool” which secretly holds the brain and the spinal cord from prying eyes.

Together with the peripheral nervous system patrolled by Lt. Swhann they keep unruly behavior to a “peep”. But ol’ were they mischievous!!! The whole lot of them!!! Sometimes after great feast prepared by the kingdom they “over-myelinate” the axon which caused a “great alarm” among the sanctity of the organism, and you never want to disturb the organism! If it were not for General Oli~go~dend~ro~cytes’ army keeping the motion of intracellular transport possible they would have long been sent away packing.

As “thought”, “hopped” through the “dendrite forest” it ran across a “sodium potassium pump”. “Thought” knew this would be a good time to “regenerate” some “sodium ions” since it had left soo much information at each “hop”. “Thought” also knew that it was also safe to cleanse the “cleft” for this would make “delay” connection during “exocytose”easier.

“Thought” knew not to go to far across the “plasma membrane” especially in this part of the “Central nervous system” because the “Sensory neurons” around these parts weren’t as permeable; and one could get “stuck” if the organism’s behavior changed.

“Thought” knew from stories around the kingdom that the Queen Hypothalamus controlled hunger and thirst and if she wanted she would unleash the hound Dopamine down the “microtubules” affecting any chances of escape.

As “thought” finished resting and was making “its” way back up to re-uptake a warning spike went out for Dopamine . This was dangerous for “thought” for it knew if nothing else but to get back in the axon and head back through the dendrite forest through the uptake if it were to make it out alive!

“Thought” suggested. “Just maybe, just maybe I can leash unto a *monoamine DAT transport vehicle, because with organism slowing down “I” cannot possibly conceive any other options”. “To the terminal button!!!" Thought wondered, as it grasped on for dear life towards the uptake. DARN!!! Thought yelled! "I’ve rested, and traveled so far, not to come back with no mitochondria from the Eukaryotic forest would just be too devasting!!!"

Back at the kingdom there was a great feast indeed. The Emperor was satisfied with the safe return of “thought” and chastised “thought” for being "sooo irresponsible" as to leave the kingdom without authority and protection. The General and his troops looked on also with great pride and ignominy but where also pleased to see “thought” safe. “Thought” as the King spoke "thought" listened quietly, and intentively, “Wisdom", as the King spoke to thought…Wisdom, is discipline…punishment is the consequence of not adhering to discipline…therefore, discipline is not punishment, and punishment is not wisdom.

...Moral of the story is “mind your elder’s”